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Stephen P Fink Selected Research

15-hydroxyprostaglandin dehydrogenase

1/2017A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.
2/2015Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.
4/2014Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).
9/2013Colonic 15-PGDH levels are stable across distance and time and are not perturbed by aspirin intervention.
4/2013Inhibition of 15-hydroxyprostaglandin dehydrogenase by Helicobacter pylori in human gastric carcinogenesis.
1/2013Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility.
5/201115-hydroxyprostaglandin dehydrogenase is downregulated and exhibits tumor suppressor activity in gastric cancer.
6/200915-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

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Stephen P Fink Research Topics

Disease

14Neoplasms (Cancer)
10/2017 - 03/2003
5Colonic Neoplasms (Colon Cancer)
10/2017 - 01/2005
4Adenoma (Adenomas)
10/2017 - 01/2005
3Colorectal Neoplasms (Colorectal Cancer)
10/2017 - 04/2014
2Carcinogenesis
09/2013 - 04/2013
1Neoplasm Metastasis (Metastasis)
10/2017
1Barrett Esophagus (Barrett's Esophagus)
01/2017
1Infections
04/2013
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
04/2013
1Inflammation (Inflammations)
01/2013
1Stomach Neoplasms (Stomach Cancer)
05/2011
1Gastritis
05/2011

Drug/Important Bio-Agent (IBA)

815-hydroxyprostaglandin dehydrogenaseIBA
01/2017 - 06/2009
4Proteins (Proteins, Gene)FDA Link
10/2017 - 01/2005
4ProstaglandinsIBA
02/2015 - 06/2009
3Biomarkers (Surrogate Marker)IBA
10/2017 - 01/2005
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
02/2015 - 09/2013
3Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
02/2015 - 09/2013
2Messenger RNA (mRNA)IBA
10/2015 - 04/2014
2AzoxymethaneIBA
02/2015 - 06/2009
2Celecoxib (Celebrex)FDA Link
02/2015 - 06/2009
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2015 - 08/2014
2Dinoprostone (PGE2)FDA Link
08/2014 - 01/2013
1Fluorescent Dyes (Fluorescent Probes)IBA
10/2017
1Vitamin DFDA LinkGeneric
01/2017
1Hyaluronic Acid (Hyaluronan)IBA
10/2015
1EnzymesIBA
02/2015
1Sulindac (Copal)FDA LinkGeneric
02/2015
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2014
1NAD (NADH)IBA
04/2014
1Hydroxyprostaglandin Dehydrogenases (Hydroxyprostaglandin Dehydrogenase)IBA
04/2014
1Oxidoreductases (Dehydrogenase)IBA
09/2013
1ErbB Receptors (EGF Receptor)IBA
04/2013
1Prostaglandins EIBA
06/2009
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
06/2009
1Uracil-DNA GlycosidaseIBA
08/2008
1EpitopesIBA
01/2005
1Transforming Growth Factor beta (TGF-beta)IBA
03/2003

Therapy/Procedure

2Chemoprevention
02/2015 - 06/2009
1Intravenous Injections
10/2017
1Therapeutics
08/2014